This Mississippi Pot Roast is a true comfort food classic. With just five main ingredients—chuck roast, ranch seasoning, au jus mix, butter, and pepperoncini—you’ll have a dish that’s rich, flavorful, and unbelievably tender. Cooked low and slow, the roast becomes fall-apart juicy, infused with tangy, buttery flavors. It’s an easy, mostly hands-off recipe that’s perfect for family dinners, meal prep, or entertaining. Serve it over mashed potatoes, noodles, or tucked into sandwiches for a meal that will have everyone asking for seconds.